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What is Biofilm

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What is Biofilm?

When bacteria and fungi adhere to a surface, they form a protective slimy layer called a biofilm.  Within the biofilm, the microorganisms are highly resistant to antimicrobial agents and host immune defenses such as white cells.  Biofilm is very important in human infections such as those involving artificial joints, vascular and urinary catheters, and chronic wounds. Biofilm is increasingly recognized to be the major factor in health and industrial problems ranging from contaminated dental and aircraft water lines to tooth decay and contact lens infections.  

Scanning electron micrograph of a biofilm on a urinary catheter

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